Require Prescription
Description:
Aclasta (Zoledronic Acid) 5mg/100ml infusion is a bisphosphonate medication used to treat a variety of bone diseases. It is primarily used to treat osteoporosis in postmenopausal women and men at increased risk of fractures, Paget's disease of bone, and to prevent skeletal-related events in patients with cancers involving the bone. Aclasta works by inhibiting the activity of osteoclasts, the cells responsible for bone resorption, thus leading to increased bone density and strength.
Ingredients:
- Active Ingredient: Zoledronic Acid 5mg
- Other Ingredients: Mannitol, Sodium Citrate, Water for Injection
Usage Instructions:
- Aclasta is administered as an intravenous infusion by a healthcare professional.
- The infusion usually takes at least 15 minutes.
- The standard dosage is 5 mg once a year for osteoporosis, or as prescribed by a healthcare provider for other conditions.
- Ensure adequate hydration before the infusion.
- Calcium and vitamin D supplementation is often recommended during treatment.
Benefits:
- Increases bone density and reduces the risk of fractures in patients with osteoporosis.
- Treats and manages Paget's disease of bone.
- Prevents skeletal-related events in patients with cancer that has spread to the bone.
- Provides long-lasting effects with a single annual infusion for osteoporosis.
Precautions:
- Not suitable for patients with severe renal impairment (creatinine clearance <35 mL/min).
- May cause acute phase reactions (fever, muscle pain, flu-like symptoms) shortly after infusion.
- Risk of osteonecrosis of the jaw, particularly in cancer patients receiving anti-cancer treatments.
- Possible side effects include hypocalcemia, musculoskeletal pain, and gastrointestinal symptoms.
- Inform your healthcare provider of any other medications or supplements you are taking.
Storage Instructions:
- Store at room temperature (20°C to 25°C or 68°F to 77°F).
- Do not freeze.
- Keep the infusion solution in its original packaging to protect from light.
- Keep out of reach of children.
Manufacturer:
Novartis Pharmaceuticals
