Description:
Advagraf 5mg is an extended-release capsule containing tacrolimus, an immunosuppressive agent. It is used to prevent organ rejection in patients who have undergone liver or kidney transplants. By reducing the activity of the immune system, Advagraf helps the body accept the transplanted organ and reduces the risk of rejection.
Ingredients:
- Active Ingredient: Tacrolimus (5mg per capsule)
- Other ingredients include: Hypromellose, lactose monohydrate, magnesium stearate, titanium dioxide (E171), ferric oxide red (E172), and ferric oxide yellow (E172).
Usage Instructions:
- Take Advagraf exactly as prescribed by your healthcare provider.
- Typically taken once daily, preferably in the morning.
- Swallow the capsules whole with a glass of water; do not crush or chew.
- Take consistently with or without food, but maintain the same condition each day.
- Regular blood tests may be required to monitor tacrolimus levels and kidney function.
- Do not skip doses; if you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double up on doses.
Benefits:
- Prevents organ rejection in liver and kidney transplant recipients.
- Helps maintain the function of the transplanted organ.
- Reduces the need for additional immunosuppressive medications.
Precautions:
- For use only under medical supervision.
- Not suitable for patients allergic to tacrolimus or any other ingredients in the capsules.
- May cause side effects such as kidney problems, high blood pressure, tremors, diabetes, and increased risk of infections.
- Inform your doctor about any pre-existing medical conditions, especially liver or kidney disease, and any other medications you are taking.
- Avoid grapefruit and grapefruit juice, as they can increase the level of tacrolimus in your blood.
- Use effective contraception during treatment and for a certain period after discontinuation, as advised by your healthcare provider.
Storage Instructions:
- Store at room temperature (below 25°C/77°F) in a dry place.
- Keep the capsules in their original container to protect from light and moisture.
- Keep out of reach of children and pets.
Manufacturer:
Astellas Pharma Inc.
