Description: Entresto 50 mg Tablets are prescribed for the treatment of heart failure with reduced ejection fraction (HFrEF). This medication combines two active ingredients to help relax blood vessels, reduce strain on the heart, and improve heart function. It is used to reduce the risk of hospitalization and death associated with heart failure.
Ingredients:
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Active Ingredients:
- 49 mg of Sacubitril (a neprilysin inhibitor)
- 51 mg of Valsartan (an angiotensin II receptor blocker)
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Other Ingredients:
- [List any excipients or additional components, such as microcrystalline cellulose, lactose monohydrate, magnesium stearate, etc.]
Usage Instructions:
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Dosage: The usual starting dose is one 50 mg tablet twice daily. The dose may be adjusted by your healthcare provider based on your response and tolerability.
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Frequency: Twice daily.
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Special Considerations: Take the tablet with or without food. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet. Consistency in taking the medication at the same time each day is recommended for optimal effectiveness.
Benefits:
- Helps improve heart function and reduce symptoms of heart failure.
- Reduces the risk of hospitalization and cardiovascular-related deaths.
- Provides a dual-action approach to treating heart failure through neprilysin inhibition and angiotensin II receptor blockade.
Precautions:
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Contraindications: Do not use if you are allergic to sacubitril, valsartan, or any other components of the tablet. Not recommended for patients with a history of angioedema related to previous ACE inhibitor or ARB therapy, or those with severe renal impairment.
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Side Effects: Possible side effects include low blood pressure, dizziness, hyperkalemia (high potassium levels), and renal impairment. Serious side effects may include angioedema and severe hypotension.
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Warnings: Regular monitoring of blood pressure, renal function, and potassium levels is essential. Inform your healthcare provider of any other medications or supplements you are taking. Use with caution in patients with a history of renal impairment or significant hypotension.
Storage Instructions:
- Store at room temperature (15°C to 25°C or 59°F to 77°F).
- Keep in a dry place away from direct sunlight and moisture.
- Keep out of reach of children.
Manufacturer: Novartis Pharmaceuticals
