Description: Kombiglyze-XR is an extended-release tablet designed to manage type 2 diabetes. It combines two active ingredients to help control blood sugar levels and improve glycemic control in adults with type 2 diabetes. The extended-release formulation provides steady medication levels throughout the day.
Ingredients:
- Active Ingredients:
- Saxagliptin 5 mg
- Metformin hydrochloride 500 mg
- Inactive Ingredients: Microcrystalline cellulose, hypromellose, magnesium stearate, polyethylene glycol, titanium dioxide, and other excipients.
Usage Instructions:
- Dosage: Typically, one tablet is taken daily.
- Frequency: Once a day, with the evening meal to reduce the risk of gastrointestinal side effects.
- Special Considerations: Swallow the tablet whole; do not crush or chew. Regular monitoring of blood sugar levels is recommended. Dosage adjustments may be needed based on blood sugar control and tolerance.
Benefits:
- Helps control blood sugar levels in patients with type 2 diabetes.
- Combines the effects of saxagliptin, which increases insulin production, and metformin, which improves insulin sensitivity and reduces glucose production by the liver.
- Extended-release formulation ensures a steady effect throughout the day.
Precautions:
- Not recommended for individuals with severe kidney impairment, diabetic ketoacidosis, or hypersensitivity to either of the active ingredients.
- Potential side effects include gastrointestinal issues such as nausea, diarrhea, and abdominal pain, as well as risk of lactic acidosis (a rare but serious condition).
- Inform your healthcare provider if you have a history of kidney disease, liver disease, heart problems, or if you are pregnant or breastfeeding.
- Regular monitoring of kidney function and blood sugar levels is advised.
Storage Instructions:
- Store at room temperature, between 20-25°C (68-77°F).
- Keep away from moisture and light.
- Do not store in the bathroom.
- Keep out of reach of children and pets.
Manufacturer:
Astra Zeneca
