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Description: Ovidrel (or Ovitrelle) is a recombinant form of human chorionic gonadotropin (hCG) used in fertility treatments. It is designed to trigger ovulation in women undergoing assisted reproductive technologies (ART) such as in vitro fertilization (IVF) or other fertility treatments. It helps to ensure the final maturation of eggs and their release from the ovaries.
Ingredients:
- Active Ingredient: Choriogonadotropin alfa (recombinant hCG) 250 mcg/0.5 ml
- Other Ingredients: Mannitol, Methionine, Poloxamer, Phosphoric acid, Sodium hydroxide, Water for injections
Usage Instructions:
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Dosage: The recommended dosage is 250 mcg administered as a single injection.
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Administration: Administer subcutaneously (under the skin) in the abdomen as directed by your healthcare provider. Follow the instructions provided with the pre-filled syringe.
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Frequency: Typically, a single injection is given at a specific time in the fertility treatment cycle as determined by your healthcare provider.
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Special Considerations: Ensure proper training on the use of the pre-filled syringe. Do not use if the solution is cloudy or contains particles. Dispose of the syringe properly after use.
Benefits:
- Triggers ovulation in women undergoing ART
- Ensures final maturation of eggs for successful fertilization
- Supports luteal phase in early pregnancy
- Convenient pre-filled syringe for ease of administration
Precautions:
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Contraindications: Not for use in individuals with hypersensitivity to hCG or any of its ingredients, primary ovarian failure, uncontrolled thyroid or adrenal dysfunction, or hormone-sensitive tumors.
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Side Effects: Common side effects include abdominal pain, headache, injection site reactions, nausea, and bloating. Serious side effects may include ovarian hyperstimulation syndrome (OHSS), multiple pregnancies, and thromboembolic events.
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Warnings: Inform your healthcare provider of any pre-existing conditions, including thyroid or adrenal gland disorders, hormone-sensitive cancers, or a history of blood clots. Regular monitoring by a healthcare provider is necessary during treatment.
Storage Instructions:
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Temperature: Store in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze.
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Humidity: Keep away from high humidity areas.
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Other Conditions: Store in the original container to protect from light. Once removed from the refrigerator, the pre-filled syringe can be stored at room temperature (up to 25°C/77°F) for a limited time as specified by the manufacturer. Keep out of reach of children.
Manufacturer: Merck Serono
