Description
Pradaxa 75 mg capsules are used for the prevention and treatment of various thromboembolic disorders. The active ingredient, dabigatran etexilate, is a direct oral anticoagulant (DOAC) that inhibits thrombin, a key enzyme in the blood clotting process. It helps prevent stroke and systemic embolism in patients with atrial fibrillation and reduces the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE).
Ingredients
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Active Ingredient: Dabigatran Etexilate (75 mg)
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Inactive Ingredients: Lactose monohydrate, magnesium stearate, pregelatinized starch, and other excipients.
Usage Instructions
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Dosage: The typical dose for patients with atrial fibrillation is 75 mg twice daily. For DVT or PE treatment, dosage may vary.
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Frequency: Twice daily.
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Special Considerations:
- Take the capsule with a full glass of water.
- Can be taken with or without food.
- Dosage adjustments may be necessary based on renal function.
- Do not discontinue or alter the dose without consulting your healthcare provider, as abrupt changes can increase the risk of blood clots.
Benefits
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Stroke Prevention: Reduces the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
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DVT and PE Management: Effective in treating and preventing recurrence of deep vein thrombosis and pulmonary embolism.
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No Routine Monitoring: Unlike some other anticoagulants, Pradaxa does not require regular monitoring of blood coagulation levels.
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Rapid Onset: Provides quick therapeutic effects due to its direct action on thrombin.
Precautions
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Contraindications: Not suitable for patients with active bleeding disorders, severe renal impairment, or known hypersensitivity to dabigatran or any of its components.
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Side Effects: Common side effects include bleeding complications, gastrointestinal symptoms (nausea, dyspepsia), and headache. Serious side effects may include severe bleeding or allergic reactions.
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Warnings:
- Monitor for signs of bleeding and seek medical attention if they occur.
- Use with caution in patients with a history of gastrointestinal bleeding or renal issues.
- Inform your healthcare provider about any other medications you are taking to avoid potential interactions, particularly other anticoagulants or antiplatelet drugs.
Storage Instructions
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Temperature: Store at room temperature between 68°F to 77°F (20°C to 25°C).
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Humidity: Keep in a dry place away from moisture.
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Other Conditions: Store in the original container, tightly closed, and protect from light.
Manufacturer Boehringer Ingelheim Pharmaceuticals, Inc.
